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Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients
المؤلفون المشاركون
Tajbakhsh, Ramin
Jushaghani, Hamid Rida
Bayzayi, Faranak
Haddad, Mahbubah
Qurbani, Mustafa
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 24، العدد 4 (31 ديسمبر/كانون الأول 2013)، ص ص. 702-706، 5ص.
الناشر
تاريخ النشر
2013-12-31
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Chronic renal disorders have a progressive course in most cases, and finally result in end-stage renal disease (ESRD).
Hemodialysis (HD) is one of the mainstays in the treatment of these patients.
Disturbance in calcium (Ca) and phosphorus (P) metabolism and alteration of serum levels of parathormone (PTH) are observed in these patients.
One of the most common cutaneous manifestations in patients on HD is pruritus.
The aim of this study is to evaluate the association between pruritus and serum concentrations of Ca, P and PTH in patients with chronic renal disease.
This analytic, descriptive, cross-sectional study was performed on 120 patients on HD at the Fifth-Azar Hospital in Gorgan, Iran, in 2010.
Information related to the patients, including age, gender, pruritus, time of pruritus and duration on dialysis, was extracted from questionnaires.
Serum concentrations of intact PTH, Ca and P were measured.
Data were analyzed by the chi-square test and SPSS-16 software.
A P-value less than 0.05 was considered statistically significant.
Among the 120 study patients, 50 % were male and the mean age (± SD) was 49 ± 12.3 years.
Sixty percent of the patients had pruritus, of whom 33.3 % had PTH levels above the normal range.
Among the 40 % of the patients who did not have pruritus, 39.6 % had PTH levels higher than the normal levels.
The mean serum Ca and P levels were 8.44 ± 1.65 mg / dL and 5.48 ± 1.81 mg / dL, respectively.
The mean (±SD) Ca-P product was 55.46 ± 47.16 and the mean PTH concentration was 274.34 ± 286.53 pg / mL.
No significant association was found between pruritus and age, sex, serum PTH and P levels as well as Ca-P product.
However, the association between serum Ca levels and pruritus was significant (P = 0.03).
Our study showed that most patients with pruritus had serum Ca levels in the abnormal range (lower or higher), and there was no significant correlation between serum iPTH level and pruritis.
Thus, good control of serum Ca levels is important to reduce pruritus in these patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tajbakhsh, Ramin& Jushaghani, Hamid Rida& Bayzayi, Faranak& Haddad, Mahbubah& Qurbani, Mustafa. 2013. Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 4, pp.702-706.
https://search.emarefa.net/detail/BIM-328606
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tajbakhsh, Ramin…[et al.]. Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 4 (2013), pp.702-706.
https://search.emarefa.net/detail/BIM-328606
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tajbakhsh, Ramin& Jushaghani, Hamid Rida& Bayzayi, Faranak& Haddad, Mahbubah& Qurbani, Mustafa. Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 4, pp.702-706.
https://search.emarefa.net/detail/BIM-328606
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 705-706
رقم السجل
BIM-328606
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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