Troponin-I is not falsely elevated in asymptomatic dialysis patients
المؤلفون المشاركون
Muij, Jaap M.
Dimirdash, Tariq M.
Mandurah, Abd Allah Y.
Husayn, Majdi M.
al-Maliki, Najla
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 24، العدد 1 (28 فبراير/شباط 2013)، ص ص. 48-53، 6ص.
الناشر
تاريخ النشر
2013-02-28
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Dialysis patients with troponin-I levels above the cut-off value diagnostic for acute myocardial event (AME) are sometimes labeled as having “ renal cause ” of elevated troponin-I.
Patients with troponin-I levels above 0.0 ng / mL, but below the cut-off level for an AME, are reported to have increased risk for coronary heart disease and mortality.
Single pre-dialysis blood samples were taken from 150 asymptomatic dialysis patients (on hemo- or peritoneal dialysis) for troponin-I, cardiac enzymes, C-reactive protein (CRP) and lipid parameters.
Troponin-I was measured by a chemiluminescent microparticle immunoassay (CMIA), of which the cut-off value for AME was set at ≥ 0.4 ng / mL.
Patients with troponin-I levels of 0.0 ng / mL, and those with levels between 0.1 and 0.3 ng / mL, were compared regarding their cardiovascular risk profile.
None of the patients had troponin-I concentrations above the cut-off level diagnostic for an AME, with 85.3 % of the patients having levels of 0.0 ng / mL.
While there was no difference in the “ traditional ” risk factors such as age, body mass index, prevalence of diabetes mellitus, hypertension, total cholesterol and low-density lipoprotein cholesterol between patients with troponin-I levels of 0.1–0.3 ng / mL and those with levels of 0.0 ng / mL, CRP concentrations were higher in the former.
In peritoneal dialysis patients, the weekly Kt / V was lower in the patients with troponin levels between 0.1 and 0.3 ng / mL.
The findings should add strong support in settling the debate of whether or not in patients on dialysis, falsely elevated levels of troponin-I “ commonly ” occur.
An increased level of CRP and lower Kt / V might add to the cardiovascular risk in patients with troponin-levels between 0.1 and 0.3 ng / mL.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Husayn, Majdi M.& Muij, Jaap M.& al-Maliki, Najla& Dimirdash, Tariq M.& Mandurah, Abd Allah Y.. 2013. Troponin-I is not falsely elevated in asymptomatic dialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 1, pp.48-53.
https://search.emarefa.net/detail/BIM-329694
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Husayn, Majdi M.…[et al.]. Troponin-I is not falsely elevated in asymptomatic dialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 1 (2013), pp.48-53.
https://search.emarefa.net/detail/BIM-329694
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Husayn, Majdi M.& Muij, Jaap M.& al-Maliki, Najla& Dimirdash, Tariq M.& Mandurah, Abd Allah Y.. Troponin-I is not falsely elevated in asymptomatic dialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 1, pp.48-53.
https://search.emarefa.net/detail/BIM-329694
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 52-53
رقم السجل
BIM-329694
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر