Chloroquine-induced acute dystonic reactions after a standard therapeutic dose for uncomplicated malaria

الملخص EN

Acute dystonic reactions (ADR) are extrapyramidal effects that usually occur after the initiation of a wide variety of drugs or triggering factors besides neuroleptics.

We report the case of a 54-year-old man who was admitted with an approximately 10-hour history of muscle twitching around the eyes, face and neck after he took the first dose of oral chloroquine phosphate (1 g [600 mg base]) prescribed for uncomplicated malaria.

He was given intravenous diazepam (10 mg statum) followed by 10 mg of oral diazepam 3 times a day.

The symptoms improved within 30 minutes of treatment, and he was discharged 14 hours later after a complete recovery.