HLA class I and class II polymorphisms and anti-nuclear antibodies in hyperprolactinaemic Iraqi females with primary infertility
المؤلفون المشاركون
al-Tamimi, Manal Badi Salih
al-Rikabi, Nahi Yusuf Yasin
al-Samirrai, Sabah Mahmud Husayn
Adhiah, Ali Husayn
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 50، العدد 4 (31 ديسمبر/كانون الأول 2008)، ص ص. 1-5، 5ص.
الناشر
تاريخ النشر
2008-12-31
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : the study was conducted to investigate the association between hyperprolactinaemia and markers of human leukocyte antigen (HLA) system in a sample of Iraqi infertile females, together with the profile anti-nuclear antibodies (ANA).
Objectives : one hundred and seventy five female patients (age range : 20 -40 years) were recruited in this study.
They were attending the Institute for Embryo Research and Infertility.
Treatment (Al-Nahrain University) during the period January 2005 - September 2006.
Results : after clinical and laboratry evaluations, it was found that 100 patients were hyperprolactinaemic, whereas the other 75 patients were euprolactinaemic, therefore, they were considered as a control group.
Based on serum level of prolactin (22-29, 30-39 and ≥ 40 Ng / ml), the total hyperprolactinaemic patients were divided into three groups; I (35 patients), II (40 patients) and III (25 patients), respectively.
The HLA antigens showed significant variations between patients (total and groups) and controls.
In total patients, B8 (25.0 vs 9.3 %), DR3 (48.0 vs.
17.3 %) and DR4 (39.0 vs.
13.3 %) showed significant increased frequencies, while B35 showed a significant decreased frequency (7.0 vs.
24 %).
The latter decrease was also observed (5.7 vs.
24.0 %) in group I of patients, which also showed a significant increased frequency of DR3 (54.3 vs.
17.3 %).
In groups II and III of patients, only DR3 (45.0 and 56.0, respectively vs.
17.3 %) and DR4 (37.5 and 56.0, respectively vs.
13.3 %) showed significant increased frequencies.
Autoantibody evaluation by ANA test revealed that 22 % of the total patients was positive, while all control subjects were negative, and such positivity paralleled the increased level of serum prolactin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adhiah, Ali Husayn& al-Tamimi, Manal Badi Salih& al-Samirrai, Sabah Mahmud Husayn& al-Rikabi, Nahi Yusuf Yasin. 2008. HLA class I and class II polymorphisms and anti-nuclear antibodies in hyperprolactinaemic Iraqi females with primary infertility. Journal of the Faculty of Medicine Baghdad،Vol. 50, no. 4, pp.1-5.
https://search.emarefa.net/detail/BIM-331584
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Tamimi, Manal Badi Salih…[et al.]. HLA class I and class II polymorphisms and anti-nuclear antibodies in hyperprolactinaemic Iraqi females with primary infertility. Journal of the Faculty of Medicine Baghdad Vol. 50, no. 4 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-331584
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adhiah, Ali Husayn& al-Tamimi, Manal Badi Salih& al-Samirrai, Sabah Mahmud Husayn& al-Rikabi, Nahi Yusuf Yasin. HLA class I and class II polymorphisms and anti-nuclear antibodies in hyperprolactinaemic Iraqi females with primary infertility. Journal of the Faculty of Medicine Baghdad. 2008. Vol. 50, no. 4, pp.1-5.
https://search.emarefa.net/detail/BIM-331584
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-331584
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر