The effect of olopatadine 0.1% ophthalmic solution on ocular and nasal symptoms in patients with seasonal allergic rhino-conjunctivitis
المؤلفون المشاركون
Qubain, Walid
Khatatbah, Ahmad
al-Zaidanin, Sulayman
المصدر
Journal of the Royal Medical Services
العدد
المجلد 20، العدد 2 (30 يونيو/حزيران 2013)، ص ص. 45-50، 6ص.
الناشر
الخدمات الطبية الملكية الأردنية
تاريخ النشر
2013-06-30
دولة النشر
الأردن
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective : to evaluate the effect of olopatadine 0.1 % ophthalmic solution twice daily on ocular and nasal symptoms in patients with seasonal allergic rhino-conjunctivitis.
Method : this study was conducted at the Ophthalmology and ear, nose and throat (ENT) clinics on patients with seasonal allergic rhino-conjunctivitis during spring and early summer seasons (March to end of June) in 2010 at Princess Haya Al Hussein hospital in the south of Jordan and in 2011 at Prince Rashid Bin Al Hassan hospital in the north of Jordan.
The patients were divided randomly into 2 groups ; group A (50 patients) received Olopatadine 0.1 % ophthalmic solution (Patanol) twice daily, group B (51 patients) received placebo in the form of balanced salt solution.
All patients attended ENT and Ophthalmology clinics weekly for 2 visits ; they were reviewed regarding the improvement of ocular symptoms (itching, redness and lacrimation) and nasal symptoms (sneezingi In those patients who received Olopatadine 0.1 % ophthalmic solution, after two weeks 98 %, 98 % and 90 % of them showed satisfactory improvement according to a scale of 1 to 5 marked by the patients for itching, lacrimation and redness respectively compared to 14 %, 12 % and 6 % in group B respectively (P-value < 0.05).
Regarding nasal symptoms 90 %, 84 % and 78 % of patients in group A showed satisfactory improvement regarding sneezing, running nose and nasal itching respectively compared to 8 %, 16 % and 10 % in group B (P-value < 0.05).
Conclusion: The treatment of ocular allergy positively impacts nasal symptoms.
The use of ocular solution of Olopatadine 0.1 % ophthalmic solution twice daily has an excellent effect on ocular symptoms and good effect on nasal symptoms, this effect was more significant at two weeks of treatment.
Olopatadine 0.1 % ophthalmic solution is a well-tolerated drug and may be considered as a primary treatment for patients with seasonal allergic rhino-conjunctivitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Qubain, Walid& Khatatbah, Ahmad& al-Zaidanin, Sulayman. 2013. The effect of olopatadine 0.1% ophthalmic solution on ocular and nasal symptoms in patients with seasonal allergic rhino-conjunctivitis. Journal of the Royal Medical Services،Vol. 20, no. 2, pp.45-50.
https://search.emarefa.net/detail/BIM-332747
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Qubain, Walid…[et al.]. The effect of olopatadine 0.1% ophthalmic solution on ocular and nasal symptoms in patients with seasonal allergic rhino-conjunctivitis. Journal of the Royal Medical Services Vol. 20, no. 2 (Jun. 2013), pp.45-50.
https://search.emarefa.net/detail/BIM-332747
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Qubain, Walid& Khatatbah, Ahmad& al-Zaidanin, Sulayman. The effect of olopatadine 0.1% ophthalmic solution on ocular and nasal symptoms in patients with seasonal allergic rhino-conjunctivitis. Journal of the Royal Medical Services. 2013. Vol. 20, no. 2, pp.45-50.
https://search.emarefa.net/detail/BIM-332747
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 49-50
رقم السجل
BIM-332747
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر