Preoperative gabapentin in laparoscopic cholecystectomy
المؤلفون المشاركون
Khayyat, Hisham S.
Said, Muhammad H.
Krikur, Anna W.
Yaqub, Zaynab A.
Yahya, Mustafa M.
المصدر
العدد
المجلد 19، العدد 1 (31 مارس/آذار 2013)، ص ص. 24-29، 6ص.
الناشر
تاريخ النشر
2013-03-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Facts in gabapentin use are known about its effect on neuropathic pain management while its clinical significance as analgesic in laparoscopic cholecystectomy has not been studied much to clarify its importance and to know how and when it could be used or if this new analgesic strategy can be an alternative to others or be as a part of multimodal analgesic therapy in postoperative management.
We conducted a prospective study to evaluate the significance of pre-emptive single dose gabapentin to reduce postoperative pain following laparoscopic cholecystectomy. Study group of hundred patients were analyzed in prospective study ; Fifty of them were gabapentin group and another fifty were placebo group.
Age, sex, body mass index, operation time and length of hospital stay were comparable in both groups.
Analgesic requirements were recorded and pain assessment using 100 visual analogue scale in both groups were studied at three times intervals of 8, 12 and 24 hours after surgery.
In addition we studied the incidence of certain postoperative side effects in both groups as nausea, vomiting and drowsiness.
Age, sex, body mass index, operation time and hospital stay were comparable in both groups. Opioid requirement two hours after surgery was significantly lower in gabapentin group than in placebo group (p < 0.05).
Also, significant difference was seen between gabapentin and placebo groups concerning the pain scores which were seen more in placebo as compared with gabapentin group in all study intervals (p < 0.05).
Significant difference between gabapentin and placebo groups was noticed regarding number of analgesic doses administered on the first 24 hours postoperatively which were more in placebo group (p < 0.05).
Insignificant difference was seen between gabapentin and placebo groups concerning certain postoperative side effects as nausea, vomiting and drowsiness (p > 0.05). In conclusion, our work shows that a single preoperative dose of gabapentin has a significant effect on postoperative pain after a laparoscopic cholecystectomy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Said, Muhammad H.& Krikur, Anna W.& Yaqub, Zaynab A.& Yahya, Mustafa M.& Khayyat, Hisham S.. 2013. Preoperative gabapentin in laparoscopic cholecystectomy. Basrah Journal of Surgery،Vol. 19, no. 1, pp.24-29.
https://search.emarefa.net/detail/BIM-335047
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Said, Muhammad H.…[et al.]. Preoperative gabapentin in laparoscopic cholecystectomy. Basrah Journal of Surgery Vol. 19, no. 1 (Mar. 2013), pp.24-29.
https://search.emarefa.net/detail/BIM-335047
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Said, Muhammad H.& Krikur, Anna W.& Yaqub, Zaynab A.& Yahya, Mustafa M.& Khayyat, Hisham S.. Preoperative gabapentin in laparoscopic cholecystectomy. Basrah Journal of Surgery. 2013. Vol. 19, no. 1, pp.24-29.
https://search.emarefa.net/detail/BIM-335047
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 29
رقم السجل
BIM-335047
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر