Optimizing object recognition task : a practical study in neurobiology by using C57BL 6 normal mice

الملخص EN

Rats and mice have a tendency to interact more with a novel object than with a familiar object.

This tendency has been used by behavioural pharmacologists and neuroscientists to study learning and memory.

A popular protocol for such research is the object-recognition task.

Animals are first placed in an apparatus and allowed to explore an object.

After a prescribed interval, the animal is returned to the apparatus, which now contains the familiar object and a novel object.

Object recognition is distinguished by more time spent interacting with the novel object.

Although the exact processes that underlie this 'recognition memory' requires further elucidation, this method has been used to study mutant mice, aging deficits, drug exposure.

This study has been conducted to optimize this method by using different objects at different times.

The results are shown by using small objects in different colures and shapes in 4 hours better than large ones in other times, which I recommend to Object Recognition Task.