Anti-inflammatory role of il-4 in patients with rheumatic mitral valve stenosis
المؤلفون المشاركون
Abd al-Muhaymin, Nidal
al-Kabi, Zaman I. L.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 52، العدد 3 (30 سبتمبر/أيلول 2010)، ص ص. 311-313، 3ص.
الناشر
تاريخ النشر
2010-09-30
دولة النشر
العراق
عدد الصفحات
3
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : IL-4 is an antibodies inflammatory cytokine which has an important role in protecting against the inflammatory reactions in most of diseases.
Here, we try to highlights the role of this cytokine in chronic Rheumatic heart disease and its correlation with the extent of histopathological abnormalities. Patients and Methods : Rheumatic mitral valve surgical fragments were taken from a total of 48 Iraqi patients with chronic rheumatic heart disease under mitral valve replacement surgery in Ibn Al-Bitar Hospital for Cardiac Surgery-Iraq-Baghdad.
Paraffin embedded mitral valve tissue sections were prepared.
IL-4-expressing cells were detected by using immunohistochemical staining technique and histopathological picture was studied by using hematoxylin and eosin staining. Results : There were lower numbers of IL-4 positive cells in all patients under study in general, but very lower IL-4 positive cells percentage was recorded in high risk group patients.
There was no significant difference in the distribution of IL-4 mean positive cell’s count among all patients (p > 0.05).
There was a correlation of IL-4 with the extent of histopathological abnormalities, and odds ratio results displayed that the histopathological abnormalities which recorded in the case group 4 times than that occurred in the control group. Conclusion : IL-4 plays an important role in regulating the inflammatory responses against the heart in chronic rheumatic heart disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Muhaymin, Nidal& al-Kabi, Zaman I. L.. 2010. Anti-inflammatory role of il-4 in patients with rheumatic mitral valve stenosis. Journal of the Faculty of Medicine Baghdad،Vol. 52, no. 3, pp.311-313.
https://search.emarefa.net/detail/BIM-335927
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Muhaymin, Nidal& al-Kabi, Zaman I. L.. Anti-inflammatory role of il-4 in patients with rheumatic mitral valve stenosis. Journal of the Faculty of Medicine Baghdad Vol. 52, no. 3 (2010), pp.311-313.
https://search.emarefa.net/detail/BIM-335927
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Muhaymin, Nidal& al-Kabi, Zaman I. L.. Anti-inflammatory role of il-4 in patients with rheumatic mitral valve stenosis. Journal of the Faculty of Medicine Baghdad. 2010. Vol. 52, no. 3, pp.311-313.
https://search.emarefa.net/detail/BIM-335927
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 313
رقم السجل
BIM-335927
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر