Serum level of adiponectin and leptin in type 2 diabetic cigarette smokers
المؤلفون المشاركون
Hamid, Ikhlas Khalid
Rashid, Nada F.
al-Kazim, Tahrir E.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 55، العدد 1 (31 مارس/آذار 2013)، ص ص. 60-63، 4ص.
الناشر
تاريخ النشر
2013-03-31
دولة النشر
العراق
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Cigarette smoking is the leading avoidable cause of morbidity and mortality in the general population ; however its effects on people with diabetes are even more profound.
The adipocytokines leptin and adiponectin play an important role in regulating glycemia, lipidemia, endothelial dysfunction, and proinflammatory mechanisms.
Objective : We aimed to investigate the profile of adiponectin and leptin in type 2 diabetic smokers and non- smokers.
Patient and Methods : Ninety overweight males attending the Teaching Laboratories, Medical City were enrolled in this study, they were arranged as 30 diabetics non smoker, 30 diabetics smokers and 30 age matched apparently healthy control group, the mean age of participants was 48.3 ± 5 years.
Fasting venous blood samples were collected from all the subjects.
The serum was used for analyzing Fasting Blood Glucose (FBG), Total cholesterol (TC), HDL-cholesterol (HDL-C), Triglycerides (TG).HbA1c was estimated by high performance liquid chromatography, LDL-cholesterol was calculated by Friedwald and Frederickson formula.
Enzyme linked immune assay were used to measure Insulin, Adiponectin and leptin.
BMI was calculated as weight in kilograms divided by height in meters squared.
Insulin resistance was calculated using HOMA-IR 1 Analysis of data was performed using the statistically package for social science (SPSS) version 17.0.
Results : Serum adiponectin and leptin level were significantly lower in the diabetics group as compared to age and BMI matched control group (7.25 ± 0.5 Vs 9.15 ± 0.3 and7.1 ± 0.6 vs.23.5 ± 6.3 respectively), Serum adiponectin and leptin level were significantly lower in diabetics who were smokers compared to the non smokers (5.5 ±0.7 Vs 8.8 ±0.9 ; p = 0.005) and (5.02 ±0.6 Vs 8 ± 0.9 ; p = 0.01 respectively), Adiponectin correlate negatively with BMI and positively with age.
Conclusion : The level of serum leptin and adiponectin were lower in diabetics who were cigarette smokers
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Kazim, Tahrir E.& Hamid, Ikhlas Khalid& Rashid, Nada F.. 2013. Serum level of adiponectin and leptin in type 2 diabetic cigarette smokers. Journal of the Faculty of Medicine Baghdad،Vol. 55, no. 1, pp.60-63.
https://search.emarefa.net/detail/BIM-336395
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Kazim, Tahrir E.…[et al.]. Serum level of adiponectin and leptin in type 2 diabetic cigarette smokers. Journal of the Faculty of Medicine Baghdad Vol. 55, no. 1 (2013), pp.60-63.
https://search.emarefa.net/detail/BIM-336395
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Kazim, Tahrir E.& Hamid, Ikhlas Khalid& Rashid, Nada F.. Serum level of adiponectin and leptin in type 2 diabetic cigarette smokers. Journal of the Faculty of Medicine Baghdad. 2013. Vol. 55, no. 1, pp.60-63.
https://search.emarefa.net/detail/BIM-336395
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 62-63
رقم السجل
BIM-336395
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر