Sodium ascorbate as green and efficient catalyst for knoevenagel condensation of aryl aldehydes with meldrum’s acid in aqueous media

الملخص EN

Sodium ascorbate (SA), acts as an efficient catalyst in the Knoevenagel condensation reaction of aryl aldehydes with Meldrum's acid in water as an environmental friendly solvent.

In this reaction, 5-arylidene-2, 2-dimethyl-1, 3-dioxane-4, 6-dione derivatives were obtained with high yields at shorter reaction periods at room temperature.

The advantages of this method are simplicity, green, safe, convenient work-up, inexpensive and readily available catalyst.