Effects of opiate dependence through different administration routes on pulmonary inflammation and its severity
المؤلفون المشاركون
Masumi, Muhammad Hasan
Tajoddini, Marzieh
Muhammadi, Gholamabbas
Malekpoor, Rida
Abbasi, Ibrahim
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 15، العدد 10 (31 أكتوبر/تشرين الأول 2013)، ص ص. 1-4، 4ص.
الناشر
تاريخ النشر
2013-10-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص AR
Background: Serious health problems and socioeconomic consequences of the illicit use of opiates have been proved in both developed and developing societies. Objectives: We aimed to evaluate "The effects of opiate addiction through different administration routes on pulmonary inflammation and its severity." Materials and Methods: Our experiments were performed on eighteen adult male Syrian golden hamsters which were allocated to one of the three groups (n = 6): control group which did not receive opiate; the first study group were administered oral opiate via stomach tube; and another study group were administered inhaled opiate.
After four weeks, all hamsters were anesthetized with diethyl ether and their lung tissues were isolated for pathological assessment. Results: Severe perivascular inflammation was detected in 33.3% of the samples with oral opiate dependence and 20% of the cases addicted to opiate through inhalation.
Also, severe peribronchial inflammation was observed in only 20% of the samples addicted to inhaled opiate and was not found in the other groups.
No significant differences were found in the severity of perivascular and peribronchial inflammation across the three groups.
Although the mean of total inflammation scale in the subjects with oral opiate dependence (3.00±1.79) was numerically higher than that in the inhaled dependence group (1.40±2.60) and the controls (2.25±1.26), this difference was not statistically significant. Conclusions: Administration did not influence the appearance or severity of pulmonary inflammation in animal models addicted to opiate.
الملخص EN
Background : Serious health problems and socioeconomic consequences of the illicit use of opiates have been proved in both developed and developing societies.
Objectives : We aimed to evaluate "The effects of opiate addiction through different administration routes on pulmonary inflammation and its severity." Materials and Methods : Our experiments were performed on eighteen adult male Syrian golden hamsters which were allocated to one of the three groups (n = 6) : control group which did not receive opiate ; the first study group were administered oral opiate via stomach tube; and another study group were administered inhaled opiate.
After four weeks, all hamsters were anesthetized with diethyl ether and their lung tissues were isolated for pathological assessment.
Results : Severe perivascular inflammation was detected in 33.3 % of the samples with oral opiate dependence and 20 % of the cases addicted to opiate through inhalation.
Also, severe peribronchial inflammation was observed in only 20 % of the samples addicted to inhaled opiate and was not found in the other groups.
No significant differences were found in the severity of perivascular and peribronchial inflammation across the three groups.
Although the mean of total inflammation scale in the subjects with oral opiate dependence (3.00 ± 1.79) was numerically higher than that in the inhaled dependence group (1.40 ± 2.60) and the controls (2.25 ± 1.26), this difference was not statistically significant.
Conclusions : Administration did not influence the appearance or severity of pulmonary inflammation in animal models addicted to opiate.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Masumi, Muhammad Hasan& Tajoddini, Marzieh& Muhammadi, Gholamabbas& Malekpoor, Rida& Abbasi, Ibrahim. 2013. Effects of opiate dependence through different administration routes on pulmonary inflammation and its severity. Iranian Red Crescent Medical Journal،Vol. 15, no. 10, pp.1-4.
https://search.emarefa.net/detail/BIM-340648
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Masumi, Muhammad Hasan…[et al.]. Effects of opiate dependence through different administration routes on pulmonary inflammation and its severity. Iranian Red Crescent Medical Journal Vol. 15, no. 10 (Oct. 2013), pp.1-4.
https://search.emarefa.net/detail/BIM-340648
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Masumi, Muhammad Hasan& Tajoddini, Marzieh& Muhammadi, Gholamabbas& Malekpoor, Rida& Abbasi, Ibrahim. Effects of opiate dependence through different administration routes on pulmonary inflammation and its severity. Iranian Red Crescent Medical Journal. 2013. Vol. 15, no. 10, pp.1-4.
https://search.emarefa.net/detail/BIM-340648
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 4
رقم السجل
BIM-340648
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر