The effect of rofecoxib and diclofenac on blood picture in male patients

الملخص EN

Objectives : To assess the effect of roficoxib and also the effect of diclofenac as a standard nonsteroidal anti-inflammatory drug (NSAD) on complete blood picture.

Methods : Complete blood picture was taken for ٢٩ male patients on roficoxib therapy at ٢٥ mg / day for ١٤-٢١ consecutive days.

Complete blood picture was also taken for ١٥ male patients on roficoxib thearapy at ١٠٠ mg / day for ١٤-٢١ consecutive days.

Comparison was made between measurements of blood picture before and at the end of treatment by using Students paired t-test.

Results : Roficoxib or diclofenac showed no significant changes in complete blood picture in the male patients in comparison with the measurements before treatment.

Conclusion : Roficoxib or diclofenac has no significant effect on blood picture in patients when used for short term with moderate doses.