Synthesis of substituted (oxazepine, diazepine, tetrazde)‎ via schiff bases for 2- aminobenzo thaizole derivatives

الملخص EN

This work includs synthesis of several Schiff bases by condensation of 6-methoxy–2-amino benzothiazole with some aldehydes and ketones (2-hydroxyl benzaldehyde, 4-hydroxyl benzaldehyde, 4- N,N –dimethy amino acetophenone, benzophenone) to abtain schiff bases (1-5).

These schiff bases were found to react with phthalate anhydride to give oxazepine derivatives (6-10) that were reacted with primary aromatic amines to give Diazepine derivatives (11-15).

Besides, we prepared new tetrazole derivatives (16-20) from the reaction of the prepared Schiff bases with sodium azide in the prepared compounds that were characterized by physical properties, FT-IR and some of the 1H-NMR and 13C –NMR spectroscopy.