Evaluation of copper, zink and magnisium in certain chronic problems

الملخص EN

Serum copper, zinc and magnesium levels were measured in 50 individuals suffering from hypertension, diabetes mellitus, chronic renal failure and laryngiocarcinoma, as 10 patients for each disease, with 10 normal control.

Patients and control were chosen at a nearly same ages in order to reduce the variation in the element ranges.

Significant decrease in serum copper concentration ( P < 0.

05 ) occurred for the hypertensive patients ( 110.

3 ± 33 ), and a highly significant increase in serum copper concentration ( P < 0.01 ) was noticed for carcinoma patients ( 172.2 ± 13 ), when each compared with the control copper concentration ( 140 ± 20 ).

Moreover, there were non significant increase in copper concentrations of diabetic and chronic renal failure patients ( 160.8 ± 33 ), (154.7± 36) respectively , ( P > 0.05 ), when compared with control copper.

Significant increase was noticed in serum zinc concentration of the patients with hypertension (147.1 ± 38 ), ( P < 0.05 ), and a highly significant decrease appear (P<0.01) in serum zinc concentration of carcinoma patients ( 59.6 ± 9 ), when they were compared with control zinc ( 110 ± 6 ).

But no significant changes ( P > 0.05 ) occurred for zinc concentrations of diabetic and chronic renal failure patients ( 115.

9 ± 48.

5 ), (101.

5 ± 50) respectively, when each compared with control zinc.

No significant changes ( P > 0.

05 ) noticed in serum magnesium concentrations of all patients in the four groups ( hypertension, diabetes mellitus, chronic renal failure and carcinoma ), ( 1.

73 ± 0.

33 ),( 1.76 ± 0.31 ),( 1.98 ± 0.

35 ), ( 1.74 ± 0.

26 ) respectively, when each compared with control magnesium ( 1.

80 ± 0.

12 ).