Synthesis and microbiological investigation of Progesterone derivatives

الملخص EN

New derivatives of progesterone were synthesized by the reaction of progesterone with hydrazine and thiosemicarbazide then cyclized by using of ethylacetoacetate and ethylallylmalonate.

The new compounds were characterized by using of Melting point and FT-IR spectroscopy.

The new compounds were tested against selected types of gram positive and gram negative bacteria,and show encarge activity.