Immunological study of patients with asthma

الملخص EN

An immunological study were performed to estimation the concentrations of immunoglobulin IgE, IL-4, IL-13 and PGE2 by ELISA, calculate the total and differential WBCs counts of patients with asthma, as well as the relationship between this disease and gender in Babylon province.

The study reveals that the IgE and I–4 levels were significantly increased (p < 0.05) in patients (second and third age categories) compared with healthy subject .

The results illustrated that the patients show a significant elevation in IL–13 levels in first (p < 0.01), second (p < 0.05) and third (p < 0.01) age categories respectively compared with control group ; furthermore, the study revealed that the concentration of prostaglandin–E2 (PGE2) show highly significant elevation (p < 0.05) in patients compared with healthy individuals.

The results displays that there is no significant differences (p < 0.05) in total WBCs count between patients and control group , and the same results was in means of neutrophils, lymphocytes and monocytes ; while there were significantly increased (p < 0.05) in eosinophils (first and second groups) and basophils (all groups) in patients compared with healthy subject , furthermore, the results reveals increased ratio of disease in females compared with males.