Study the ability of using sesame oil as an adjuvant

الملخص EN

The aim of the present study is to investigate the ability of sesame seed oil as an adjuvant by intramuscular injection of laboratory rabbits with 1ml of sesame oil conjugate with 1mg capsular polysaccharide of Streptococcus pneumonia serotype 2.

The serum (systemic) and trachea (mucosal specific immunoglobulin titer of rabbits after 7, 15 and 21 days was measured.

The results demonstrated that there was significant increase (p = 0.0499) in specific serum immunoglobulin titer of rabbits (106.67) and in trachea of rabbits (46.66) post days from administration.

Also the results proved that there was significant increase (p = 0.0481) in specific serum immunoglobulin titer of rabbits (213.333) post 21 days administration as compared to controls (106.76).

The study recommended that the sesame oil can act as an adjuvant through inducing high level of specific serum immunoglobulin titer of rabbits.