Possible role for interleukin-5 in asthma

الملخص EN

Background : Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators.

Among those mediators are the cytokines such as IL-5.

Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method.

Results & Conclusions : There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls (P < 0.

001).

We conclude that this cytokine may play the major role in asthmatic attack & it may be a good marker for the disease.