Square wave voltammetry determination of coenzyme Q10

الملخص EN

An easy and extremely sensitive square wave voltammetric method for the determination of coenzyme Q10 has been evolved.

The method is based on the direct measurement of the reduction peak current of the coenzyme Q10 at (-0.20 V)[(Ep) versus the Ag/AgCl reference electrode) at (pH = 7.3) and (25°C).

The magnitude of the reduction peak current (at Ep) has been found to be related to the concentration of the coenzyme over the range of (8.8 x 10-8 – 5.4 x 10-7 M) (r = 0.9893) and the relative standard deviation of the method at the (1.3 x 10-7 M) [113 ppb] level is (± 3.9 %) [n (number of samples) = 6].

The presence of albumin with CoQ10 causes a large depression in the reduction peak current of the coenzyme and its (Ep) moves to (-0.18 V).