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Lipid peroxidation, prooxidant and related antioxidant proteins in various types of hyperlipoproteinemic males and control
العناوين الأخرى
الأكسدة الفوقية للدهون، مسببات الأكسدة و مضادات الأكسدة البروتينية ذو العلاقة في أنواع مختلفة من ارتفاع البروتينات الدهنية من الذكور
المؤلف
المصدر
Ibn al-Haitham Journal for Pure and Applied Science
العدد
المجلد 23، العدد 1 (30 يونيو/حزيران 2010)11ص.
الناشر
جامعة بغداد كلية التربية ابن الهيثم
تاريخ النشر
2010-06-30
دولة النشر
العراق
عدد الصفحات
11
التخصصات الرئيسية
الموضوعات
الملخص AR
شملت الدراسة الحالية تسعة و ثلاثين من الذكور يعانون من ارتفاع الدهون في الدم تتراوح أعمارهم بين (48-63) سنة لا يتعاطى أي منهم علاجا” خافضا" لدهون الدم و المراجعين في العيادة الخارجية لمستشفى بغداد التعليمي، فضلا عن أثنين و عشرين من الذكور ذي مستويات دهون طبيعية في أمصالهم مقاريين في العمر يوصفهم مجموعة سيطرة.
الملخص EN
Thirty nine hyperlipoproteinemic (HPLic) male subject aged (48-63) year not on any of the lipid lowering drugs, attending out patient clinic at Baghdad Teaching Hospital, were included in the present study, in addition to twenty two normolipidimic male subjects of matched age were included as control throughout this study.
The first part of this study was devoted to the classification of the HPLic subjects according to the serum lipid and lipoprotein profile following defined criteria.
The lipid parameter including total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL) were investigated in serum of HPLic subjects included in the study.
The classification was performed according to Frederickson's type, as twenty one hypercholesterlemic (type IIa), and eighteen hypertriglycerdimia (type IV) HPLic subjects.
In the second part of the study, lipid peroxidation marker measured as malondialdehyde (M DA), free iron, ferritin, transrerrin (Tf) and ceruloplasmin (Cp) levels were measured in the serum of all subjects included in the study.
The results indicated that significant increase was observed in the serum levels of Tc, Tg and LDL in type IIa and Type IV HPLic compared to control, and a significant decrease in HDL level in serum of both HPLic group compared to control, while no significant difference in serum HDL levels between type IIa and ty pe IV HPLic was found.
The mean MDA, free iron and ferritin levels in serum were found to be significantly higher in both types IIa and IV HPLic compared to control, also ferritin level in serum of type IV showed a significant increase over that of type IIa (257.3±22.7 vs.
223±19.2 mg/ml; p<0.05).
On the other hand, no significant difference in mean MDA and free iron levels between both types of HPLic groups were found.
The mean Tf and Cp levels in serum of ty pe IIa HPLic group showed a slight increase, yet not significant when compared to control, but a non significant decrease in Tf and Cp levels in serum of type IV HPLic group compared to control was found, however neither Tf nor Cp levels showed any significant difference between both HPLic groups.
These results suggest the presence of oxidative stress injury in subjects with either ty pe IIa or IV HPL, which could be due to high levels of LDL which is more susptible to oxidation and high levels of serum free iron which act as a prooxidant agent in its free form.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Tai, Wafa Fadil. 2010. Lipid peroxidation, prooxidant and related antioxidant proteins in various types of hyperlipoproteinemic males and control. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 23, no. 1.
https://search.emarefa.net/detail/BIM-354295
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Tai, Wafa Fadil. Lipid peroxidation, prooxidant and related antioxidant proteins in various types of hyperlipoproteinemic males and control. Ibn al-Haitham Journal for Pure and Applied Science Vol. 23, no. 1 (2010).
https://search.emarefa.net/detail/BIM-354295
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Tai, Wafa Fadil. Lipid peroxidation, prooxidant and related antioxidant proteins in various types of hyperlipoproteinemic males and control. Ibn al-Haitham Journal for Pure and Applied Science. 2010. Vol. 23, no. 1.
https://search.emarefa.net/detail/BIM-354295
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendices.
رقم السجل
BIM-354295
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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