Synthesis of new derivatives of p-lactam antibiotics

الملخص EN

New Der؛vat؛ves for Known P- lactam ant؛b؛©t؛cs were synthesized utilizing the free amino group present in the parent compounds as the site for derivat؛zat؛on.

The oh]ecti^es for this study are to have new compounds which could have an increased potential resistance to the de§radative enzymes knowing to be able to destroy the antibacterial activity of p- lactam antibiotics - Besides, these new derivatives could be congeners of known agents, or may be a potential pro-drugs for these agents