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Nasopharyngeal carcinomas : prognostic factors and treatment features
المؤلفون المشاركون
Aribas, Bilgin Kadri
Cetindag, Fayiq
Ozdogan, Zafir
Dizman, Aysin
Demir, Pelin
Unlu, Dilek Nil
Yologlu, Zeynel
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 20، العدد 3 (30 سبتمبر/أيلول 2008)، ص ص. 230-236، 7ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2008-09-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Purpose : We retrospectively evaluated the clinical, radiological and pathological features determining the prognosis of patients with nasopharyngeal carcinoma in Ankara Oncology Hospital, Turkey.
Material and Methods : Two hundred and fifty-nine patients, 74 women and 185 males with nasopharyngeal carcinoma were treated between 1993 and 2008.
All imaging data including CT and MRI were reevaluated according to the criteria which determine parapharyngeal, oropharyngeal, nasal, skull-base (bone)/sinus, infratemporal fossa, orbit, intracranial involvements and lymph node metastasis by our radiologists.
The patients were restaged using the AJCC 2002 classification with these new radiological findings and clinical data base.
We evaluated prognostic factors using univariate Kaplan- Meier and multivariate Cox regression analyses.
Gender, age (40-year cut-off), histology, T- and N-stage, tumor size, regional involvement, radiotherapy and/or chemotherapy and response to therapy were studied as variables.
Results : Five-year disease-free and overall survival rates were 45±4% and 72±3%, respectively.
We found that age, gender, WHO type, radiotherapy and/or chemotherapy, N-stage and response to therapy were significant prognostic factors on disease-free survival and overall survival.
In the chemo-radiotherapy group, we did not detect any survival difference between patients given four or fewer chemotherapy courses.
Conclusions : Radiotherapy improved survival but chemotherapy, in the neoadjuvant and adjuvant setting, had no added effect to radiotherapy.
N-stage and response to treatment were the most important independent predictors on survival.
Age, gender, type, therapy and bone/sinus involvement were among the predictive factors on multivariate analysis, as well.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aribas, Bilgin Kadri& Cetindag, Fayiq& Ozdogan, Zafir& Dizman, Aysin& Demir, Pelin& Unlu, Dilek Nil…[et al.]. 2008. Nasopharyngeal carcinomas : prognostic factors and treatment features. Journal of the Egyptian National Cancer Institute،Vol. 20, no. 3, pp.230-236.
https://search.emarefa.net/detail/BIM-355884
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aribas, Bilgin Kadri…[et al.]. Nasopharyngeal carcinomas : prognostic factors and treatment features. Journal of the Egyptian National Cancer Institute Vol. 20, no. 3 (Sep. 2008), pp.230-236.
https://search.emarefa.net/detail/BIM-355884
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aribas, Bilgin Kadri& Cetindag, Fayiq& Ozdogan, Zafir& Dizman, Aysin& Demir, Pelin& Unlu, Dilek Nil…[et al.]. Nasopharyngeal carcinomas : prognostic factors and treatment features. Journal of the Egyptian National Cancer Institute. 2008. Vol. 20, no. 3, pp.230-236.
https://search.emarefa.net/detail/BIM-355884
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 236
رقم السجل
BIM-355884
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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