Clinical evidence : the prolonged dust exposure the disorder in serum oxidant-antioxidant balance

الملخص EN

Dust uan be considered as an important factor in environmental pollution which has a direct efleet on human health.

In this study ,we attempted to evaluate serum oxidant -antioxidant balance in workers dust exposed continuously and also the effect of iron and silicon content in exposed dust on the mentioned balance .The study included three groups: A group included 20 workers of building block factories, B group included 20 workers ١١؛ general company of grains production and c group included I ؤ healthy subjects ؛١٧١٦^ represented control group.

Iron and silicon contents in dust samples of two studied regions were measured.

Higher levels of iron and silicon were found ١٦؛ A group region compared to ة group region.

Our results illustrated a significant elevation in serum (MDA) levcl(the index of lipid peroxidation) for A group compared to Band c groups.

Also, a significant dccrcase ١١٦ sertim albumin level was found in ٨ group compared to c group as well as serum ceruloplasmin level in ٨ group was found to be significantly elevated compared to B and c groups.

A negative con-elation was found between serum N'tDA and scrum albumin levels in A and B groups.

Also ,positive correlations were found between serum MDA and each of serum œruloplasmin and daily dust exposure time ١٦؛ A and ة groups.

These results provide a new conclusion that the iron and silicon content in prolonged exposed dust lead to disorder in serum oxidant - antioxidant balance.s