A study of some cellulose derivatives as hydrogel for control drug release

الملخص EN

Neutral and semi-synthetic hydrophilic polymers are widely used in pharmaceutical technology to formulate as controlled release drugs delivery systems ,cellulose derivatives is biocoin^tibility, biodegradability , non-toxicity, its is a good candidate as drug carrier.

In this study, polymers were used as cellulose derivatives like -Methylcellulose (MC) ه Sodium Carbox^^tlty'lcellulose (NaCMC) as hydrogels for controlled delivery fortwo kinds of drugs, Cefotaxine & Amoxycilline trihydrate in different media (Distilled water, Normal Saline & Bul'fer solution PH=2).

It has been shown that ،٠٠١• sodium Carboxymethylcellulose the drug release rate is more than the Mcthylcellulose and that the release rate for Amoxycilline trihydratc is more than Cefotaxine.