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Metabolic status of 1088 patients after renal transplantation : assessment of twelve years monitoring in Algiers Mustapha Hospital
المؤلفون المشاركون
Yargui, Lyece
Chettouh, Huriyyah
Boukni, Hamamah
Mukhtari, Nasimah
Berhoune, Arezki
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 25، العدد 1 (28 فبراير/شباط 2014)، ص ص. 177-184، 8ص.
الناشر
تاريخ النشر
2014-02-28
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
-Since the introduction of monitoring levels of immunosuppressive medications in our service in July 2000, 1088 kidney transplant patients were received for therapeutic drug monitoring and regular follow-up.
The aim of this study was to retrospectively analyze the data on these renal graft patients in Algeria and correlate with our 12 years’ experience with calcineurin inhibitor (CNI) measurements.
In addition, during this period, we also examined other biochemical parameters.
The analysis was focused on the difference of effect of cyclosporin A (CsA; 623 patients) and Tacrolimus (Tac; 465 patients) on lipid and glucose metabolism and their sideeffects, if any, on the renal function.
The mean age at the time of transplantation was 36.1 years.
A great majority of the transplanted kidneys had been taken from living related donors (88.6%).
Three-quarters of all grafts were transplanted in our country (79.5%).
Dyslipidemia and renal dysfunction were the most common adverse effects of CsA and Tac exposure, with a frequency of 21.4% and 10.3%, respectively.
Both the CNIs had a similar effect on the lipid levels.
The highest incidence occurred at 3–12 months after renal graft.
Tac seemed to have more side-effects on glycemia, causing the onset of diabetes mellitus more than two-fold than CsA (6.9% vs.
3.1%).
A significant difference was observed during 12–24 months after transplantation.
However, Tac was associated with the most favorable effects on renal function estimated with the Modification of Diet in Renal Disease (MDRD) formula.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yargui, Lyece& Chettouh, Huriyyah& Boukni, Hamamah& Mukhtari, Nasimah& Berhoune, Arezki. 2014. Metabolic status of 1088 patients after renal transplantation : assessment of twelve years monitoring in Algiers Mustapha Hospital. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 1, pp.177-184.
https://search.emarefa.net/detail/BIM-357073
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mukhtari, Nasimah…[et al.]. Metabolic status of 1088 patients after renal transplantation : assessment of twelve years monitoring in Algiers Mustapha Hospital. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 1 (Jan. / Feb. 2014), pp.177-184.
https://search.emarefa.net/detail/BIM-357073
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yargui, Lyece& Chettouh, Huriyyah& Boukni, Hamamah& Mukhtari, Nasimah& Berhoune, Arezki. Metabolic status of 1088 patients after renal transplantation : assessment of twelve years monitoring in Algiers Mustapha Hospital. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 1, pp.177-184.
https://search.emarefa.net/detail/BIM-357073
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 183-184
رقم السجل
BIM-357073
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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