Antioxidant effect of vitamin e treatment on some heavy metals-induced renal and testicular injuries in male mice
المؤلف
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 18، العدد 1 (31 مارس/آذار 2011)، ص ص. 63-72، 10ص.
الناشر
تاريخ النشر
2011-03-31
دولة النشر
السعودية
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Toxic heavy metals in water, air and soil are global problems that are a growing threat to humanity.
Heavy metals are widely distributed in the environment and some of them occur in food, water, air and tissues even in the absence of occupational exposure.
The antioxidant and protective influences of vitamin E on a mixture of some heavy metals (Pb, Hg, Cd and Cu)-induced oxidative stress and renal and testicular injuries were evaluated in male mice.
Exposure of mice to these heavy metals in drinking water for seven weeks resulted in statistical increases of plasma creatinine, urea and uric acid concentrations.
The levels of glutathione (GSH) and superoxide dismutases (SOD) in kidney and testis tissues were significantly declined.
Moreover, the histopathological evaluation of kidney and testis showed severe changes in mice treated with these heavy metals.
Administration of vitamin E protected the kidney and testis of mice exposed to heavy metals as evidenced by appearance of normal histological structures, insignificant changes in the values of plasma creatinine, urea and uric acid, and the levels of kidney GSH and SOD, while the levels of testis GSH and SOD were notably decreased.
These data suggest that the administration of vitamin E protects against heavy metals-induced renal and testicular oxidative stress and injuries.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Attar, Atif M.. 2011. Antioxidant effect of vitamin e treatment on some heavy metals-induced renal and testicular injuries in male mice. Saudi Journal of Biological Sciences،Vol. 18, no. 1, pp.63-72.
https://search.emarefa.net/detail/BIM-357583
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Attar, Atif M.. Antioxidant effect of vitamin e treatment on some heavy metals-induced renal and testicular injuries in male mice. Saudi Journal of Biological Sciences Vol. 18, no. 1 (2011), pp.63-72.
https://search.emarefa.net/detail/BIM-357583
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Attar, Atif M.. Antioxidant effect of vitamin e treatment on some heavy metals-induced renal and testicular injuries in male mice. Saudi Journal of Biological Sciences. 2011. Vol. 18, no. 1, pp.63-72.
https://search.emarefa.net/detail/BIM-357583
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p.70-72
رقم السجل
BIM-357583
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر