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Image analysis assessment of fibrosis from liver biopsy of chronic hepatitis patients
المؤلفون المشاركون
Farraj, Abd al-Raziq H.
Mari, Naima A.
Hilmi, Dina O.
Badawi, Manal A.
Sulayman, Ahmad S. A.
المصدر
Journal of the Arab Society for Medical Research
العدد
المجلد 7، العدد 2 (31 ديسمبر/كانون الأول 2012)، ص ص. 48-56، 9ص.
الناشر
تاريخ النشر
2012-12-31
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
Liver fibrosis results from chronic inflammation of the hepatic parenchyma.
Progressive accumulation of fibrous tissue eventually leads to cirrhosis and its complications.
The severity of liver fibrosis defines the stage of chronic hepatitis and carries with it important clinical implications.
Histological scoring systems such as Ishak provide descriptive evaluation of the liver tissue mainly in terms of architectural changes without measuring the amount of fibrosis.
This study aimed to assess the theoretical advantage of image analysis morphometry for providing truly quantitative data with respect to the amount of fibrous tissue.
Materials and methods A Lieca Qwin 500 image analyzer with a damaged area morphometry software was used applying the interactive method to measure the fibrous tissue area on the basis of different colors of hepatocytes and fibers following staining with Masson’s trichrome stain.
Forty-three patients (38 men and five women) were recruited into the study with a mean age of 45.5 years (range 15–58 years).
Of them, 40 had chronic viral hepatitis and three had chronic nonviral hepatitis.
Results Morphometric measurements of fibrosis obtained with the image analyzer were highly correlated with results obtained using the Ishak method.
The correlation was found to be statistically significant using the w2-test (Po0.0001).
Conclusion Quantitative image analysis for estimation of the percentage area of liver fibrosis is a simple and accurate method for evaluating fibrous tissue in patients with chronic hepatitis, aiding therapeutic approaches.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mari, Naima A.& Hilmi, Dina O.& Badawi, Manal A.& Farraj, Abd al-Raziq H.& Sulayman, Ahmad S. A.. 2012. Image analysis assessment of fibrosis from liver biopsy of chronic hepatitis patients. Journal of the Arab Society for Medical Research،Vol. 7, no. 2, pp.48-56.
https://search.emarefa.net/detail/BIM-359037
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mari, Naima A.…[et al.]. Image analysis assessment of fibrosis from liver biopsy of chronic hepatitis patients. Journal of the Arab Society for Medical Research Vol. 7, no. 2 (2012), pp.48-56.
https://search.emarefa.net/detail/BIM-359037
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mari, Naima A.& Hilmi, Dina O.& Badawi, Manal A.& Farraj, Abd al-Raziq H.& Sulayman, Ahmad S. A.. Image analysis assessment of fibrosis from liver biopsy of chronic hepatitis patients. Journal of the Arab Society for Medical Research. 2012. Vol. 7, no. 2, pp.48-56.
https://search.emarefa.net/detail/BIM-359037
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 55-56
رقم السجل
BIM-359037
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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