Evaluation of micronucleus frequency by acridine orange fluorescent staining in bucccal epithelial cells of oral submucosus fibrosis (OSMF) patients
المؤلفون المشاركون
Afzal, Muhammad
Naz, Falaq
Jyoti, Smita
Sadiq, Yasir Hasan
Khan, Sayf
المصدر
The Egyptian Journal of Medical Human Genetics
العدد
المجلد 14، العدد 2 (30 إبريل/نيسان 2013)، ص ص. 189-193، 5ص.
الناشر
الجمعية المصرية للأمراض الوراثية
تاريخ النشر
2013-04-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Oral submucosus fibrosis (OSMF) is a collagen-related disorder seen in habitual betel quids and smokers.
This is a high risk precancerous condition in which the connective tissue fibers of the lamina propria and deeper parts of the mucosa becomes stiff with restricted mouth opening.
Patients with severe cases have symptoms like difficulties in chewing, swallowing and speaking.
In the present study 25 individuals were gutkha chewers and 25 were OSMF patients (chewing gutkha along with smoking) and 25 individuals were taken as controls.
A significant increase in the frequency of micronuclei was observed in OSMF patients (34.4 ± 1.79) as compared to gutkha chewers (14.4 ± 0.73) and controls (4.36 ± 0.27).
The number of micronucleated cells in OSMF, gutkha chewers and control groups were 19.84 ± 0.69, 12.6 ± 0.51 and 4.20 ± 0.27, respectively and are significantly different at p < 0.05.
Acridine orange is used due its fluorescence nature and easier visibility of the micronucleus present in the buccal epithelial cells.
It is concluded that chewing gutkha along with smoking is more dangerous for human health as it hastens the incidence of OSMF.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jyoti, Smita& Khan, Sayf& Afzal, Muhammad& Naz, Falaq& Sadiq, Yasir Hasan. 2013. Evaluation of micronucleus frequency by acridine orange fluorescent staining in bucccal epithelial cells of oral submucosus fibrosis (OSMF) patients. The Egyptian Journal of Medical Human Genetics،Vol. 14, no. 2, pp.189-193.
https://search.emarefa.net/detail/BIM-359617
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jyoti, Smita…[et al.]. Evaluation of micronucleus frequency by acridine orange fluorescent staining in bucccal epithelial cells of oral submucosus fibrosis (OSMF) patients. The Egyptian Journal of Medical Human Genetics Vol. 14, no. 2 (Apr. 2013), pp.189-193.
https://search.emarefa.net/detail/BIM-359617
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jyoti, Smita& Khan, Sayf& Afzal, Muhammad& Naz, Falaq& Sadiq, Yasir Hasan. Evaluation of micronucleus frequency by acridine orange fluorescent staining in bucccal epithelial cells of oral submucosus fibrosis (OSMF) patients. The Egyptian Journal of Medical Human Genetics. 2013. Vol. 14, no. 2, pp.189-193.
https://search.emarefa.net/detail/BIM-359617
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 192-193
رقم السجل
BIM-359617
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر