Diabetes mellius is the predominant risk factor of Dupuytren’s disease in Babylon aprospective matched case control study

الملخص EN

In Merjan teaching hospital we recorded (3200) cases of hand complaints in period from Nov.

2002-June 2004.

Of them, Dupuytren’s hand diseases were represented in (84) cases 2.6% the (study group).

which were investigated for the association and severity, with diabetes mellitus ,smoking and other risk factors , this study group also were matched for age and gender with other three groups : Group I: (230) Patients who had diabetes mellitus for more than (10) years duration, who were neither smokers nor alcoholic or epileptics.

Group II: (300 ) community controls , who were smokers “ more than 20 cigarette per day for more than 10 years “,who were neither diabetics nor alcoholic or epileptics .

Group III: ( 420 ) community controls , who were randomly selected .

The results showed that the Dupuytren’s disease is strongly associated with diabetes mellitus, where in study group: 25% of Dupuytren’s were diabetics, while 11.9% of Dupuytren’s were smokers 2.3% were epileptics on phenytoin.

Group I: 9.5% of diabetics patients had got Dupuytren’s Group II :2.6% of smokers had got Dupuytren’s disease .

Group III: The total number of Dupuytren's disease were ( 7 ) cases 1.6 %.

Grouped as follow ( 4 ) cases were diabetics , ( 1 ) case was smokers.

And (2) cases had not apparent risk factors .

On basis of the results, the Dupuytren’s disease is strongly associated with diabetes mellitus, although milder , appeared earlier in age than other risk factors and mostly bilateral.

There was no significant difference regarding incidence between different types of jobs , or between dominant hands and non dominant ones .

The purpose of the present prospective case matched study , is to elucidate the role of diabetes mellitus as main predisposing risk factor of Dupuytren’s disease In Babylon.