Possible role of interleukins 6 and 10 in colorectal carcinoma in Iraqi patients

الملخص EN

Background : It is quite accepted that interleukins (IL) in general play a crucial role in response to injuy , infection and on cogenic trans formation , among there are IL-6 and ILJO.

Aim of this study is to find out the possible role of IL_ and IL, 10 in colo rectaI carcima in Iraqi patients.

Subjects and Methods: forty patients with colorectal cancer (CRC) composed with 30 healthy controls were enrolled in this study.

Serum conc.

Of IL-6 and IL -lOwere estimated in both groups using ELIZA technique.

Results: Serem levels of IL-6 and IL-10 were significantly increased (P<0.001) in compassion with control group.

Conclusion: these cytokins could be used as a markers for tumor progression .