Antibacterial potential of elected Sudanese medicinal plants against upper respiratory tract pathogens

مقدم أطروحة جامعية

Dawud, Munir Fathi Muhammad

مشرف أطروحة جامعية

al-Kamali, Hatil Hashim

الجامعة

جامعة أم درمان الإسلامية

الكلية

كلية العلوم و التقانة

القسم الأكاديمي

قسم النبات

دولة الجامعة

السودان

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2005

الملخص الإنجليزي

The ethanolic, petroleum ether, ethyl acetate, methanolic and water extracts of the 13 Sudanese medicinal plants Acacia nilotica ssp.

nilotica (pods, flowers and stem bark), Citrus paradisi (internal peel of fruit), Croton zambesicus (fruits), Eucalyptus camaldulensis (leaves), Hibiscus sabdariffa (calyces), Sphaeranthus suaveolens (herb), Psidium guajava (leaves), Ziziphus spina-christi (fruits), Acacia seyal (stem bark), Combretum hartmannianum (stem bark), Terminalia brownii (stem bark), Syzygium cumini (stem bark) and Mangifera indica (stem bark) were investigated for its antibacterial activity against seven standard strains of bacteria commonly associated with respiratory infections Streptococcus pyogenes (ATCC 12344), Streptococcus pneumonia (ATCC 6305), Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Klebsiella pneumoniae (ATCC 15380) and Haemophilus influenzae (ATCC 10211) in vitro.

Microorganism were plated in nutrient agar.

Plant extracts at a concentration of 100 mg/ml were applied using the agar plate well-diffusion method.

The high antibacterial activity was found in ethanol and methanol extracts, the lowest in ethyl acetate.

The potentially more interesting species were Acacia nilotica ssp.

nilotica, Hibiscus sabdariffa, Acacia seyal and Sphaeranthus suaveolens for their broad spectrum of activity and Acacia nilotica ssp.

nilotica that produced a large zone of inhibition against Gram-negative bacteria and S.

aureus among Gram-positive bacteria.

Maximum activity was observed against E.

coli and K.

pneumoniae.

Compared to reference antibiotics, some candidate plant species exhibited broader spectrum of antibacterial activity and were found to be clearly superior in case of A.

nilotica ssp.

nilotica, Hibiscus sabdariffa and Acacia seyal.

These findings should stimulate the search for novel, natural product such as antibacterial agent.

التخصصات الرئيسية

الأحياء

الموضوعات

• النباتات الطبية
• الأمراض الجرثومية
• العلاج الكيميائي
• السودان
• المواد المضادة للبكتيريا

عدد الصفحات

120

قائمة المحتويات

• APA
• MLA
• AMA

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-364736