Phytochemistry and antimicrobial activity of Lepidium sativum L. seeds and Prunus mahaleb L. seeds
مقدم أطروحة جامعية
مشرف أطروحة جامعية
al-Maqbul, Aishah Zuhayr
Abd al-Majid, Muna Abd al-Munim Muhammad
الجامعة
جامعة أم درمان الإسلامية
الكلية
كلية الصيدلة
القسم الأكاديمي
قسم العقاقير الطبيعية
دولة الجامعة
السودان
الدرجة العلمية
ماجستير
تاريخ الدرجة العلمية
2009
الملخص الإنجليزي
Phytochemical screening and antimicrobial activities were investigated for two Sudanese traditional medicinal plants which were authenticated at the Medicinal and Aromatic Plants Research Institute (MAPRI).
Extracts of Lepidium sativum seeds (Brassicaceae),and Prunus mahaleb seeds (Rosaceae).were screened for their antimicrobial activity against fourstandard bacteria : two Gram positive (Bacillus subtilis, Staphylococcus aureus), two Gramnegative (Escherichia coli, Pseudomonasaeruginosa) andtwo standard fungal strains namely Aspergillus nigerandCandida albicans. The organic extracts of Lepidium sativum and Prunus mahaleb exhibited low activity against all bacterial strains tested except the benzene extract of Prunus mahalebwhich exhibited intermediate activity.
On the other hand, the oil which was fractionated from the Lepidium sativum chloroform extract showed high activity to full inhibition growth against both Gram positive (Bacillus subtilis, Staphylococcus aureus) and two fungi tested (Aspergillus nigerandCandida albicans).
The standard organisms were tested against reference antibacterial and antifungal drugs and the results were compared with the activity of the chloroform oily fraction of Lepidium sativum. The seeds ofLepidium sativum andPrunus mahaleb were phytochemically screened to detect the presence of the secondary metabolites.
Unsaturated sterols and Triterpenses, Alkaloids,Flavonoids, Tannins, Anthraquinone glycosides were detected on both plants.
Saponins were present only in Lepidium sativum.
WhileCoumarins and Cyanogenic glycosides were detected onPrunus mahaleb only. The chloroform oily fraction of Lepidium sativum was developed on T.L.C using stationary phase (Silica gel type DG), and two moving phases {(Toluene : Ethyl acetate (93 : 7),( Petroleum ether : Diethyl ether (90 : 10)}.
The results reflected the presence of 14 compounds.
These compounds were detected using GC / MS (for the fraction) as (Cyclotetrasiloxane,octamethyl-.
; Pyrido {2,3-glindole,5-methoxy-2,3,7,9-tetramethyl} ; Cyclopentasiloxane, decamethyl ; Benzonitrile,2-methyl-.
; Bicyclo {4.1.0} hepta-2,4-diene ,2,3,4,5-tetraethyl-7,7-diphenyl.
; m-Tolyl isothiocyanate .
; 2 (1H)-Quinoxalinone.
; Pentasiloxane,1,1,3,3,5,5,7,7,9,9-decamethyl ; 1,3,5-Tris(trimethylsiloxy) benzene ; 2,4,6-Cycloheptatrien-1-one,3,5-bis-trimethylsilyl ; Acetic acid, [bis {(trimethlsilyl) oxy}phosphinyl]-,trimethylsilyl ester ; Dibutyl phthalate ; Heptasiloxane,1,1,3,3 ,5,5,7,7,9,9,11,11,13,13-tetradecamethyl.
; Thiazol-2-amine,4-(6-methylimidazol [2,1-b]thiazol-5-yl) (-N-)2-pyridy1.
التخصصات الرئيسية
الموضوعات
عدد الصفحات
107
قائمة المحتويات
Table of contents.
Abstract.
Chapter One : Introduction and literature review.
Chapter Two : Materials and methods.
Chapter Three : Results.
Chapter Four : Discussion and conclusion and recommendations.
References.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khayri, Tilal Ahmad Salih. (2009). Phytochemistry and antimicrobial activity of Lepidium sativum L. seeds and Prunus mahaleb L. seeds. (Master's theses Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-366363
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khayri, Tilal Ahmad Salih. Phytochemistry and antimicrobial activity of Lepidium sativum L. seeds and Prunus mahaleb L. seeds. (Master's theses Theses and Dissertations Master). Omdurman Islamic University. (2009).
https://search.emarefa.net/detail/BIM-366363
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khayri, Tilal Ahmad Salih. (2009). Phytochemistry and antimicrobial activity of Lepidium sativum L. seeds and Prunus mahaleb L. seeds. (Master's theses Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-366363
لغة النص
الإنجليزية
نوع البيانات
رسائل جامعية
رقم السجل
BIM-366363
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر