Pattern of acute lymphoblastic leukemia among Kurdish children in Duhok City, Northern Iraq

الملخص EN

Although it is a common malignancy, there is a lack of information about leukemias in Kurdish people.

To evaluate the pattern of acute lymphoblastic leukemia among Kurdish children in Duhok city / North of Iraq, and to compare it with available data from other countries, 83 cases were studied of acute lymphoblastic leukemia diagnosed by bone marrow aspiration cytology, cytochemistry and immune-phenotyping between July 2006 and August 2010.

Data recorded included age, sex, area of residence whether rural or urban, socio-economic status, the presenting features and the initial peripheral blood and bone marrow findings.

Ages ranged from 7 months to 14.5 years, the peak occurrence was between one and five years and the male to female ratio was 1.7 : 1.

Most patients were low socio-economic class (86.7 %), and 68 % were living in rural areas.

The most frequent presenting features were pallor (88%) and bleeding tendency (65%), and 25.2% of patients had a leukocyte count above 50,000 per cubic millimetre.

L1 and L2 morphology was approximately equal (51.6% and 46.9%, respectively).

The percentage of T-cell ALL was higher than the range reported in other countries.

Conclusion: Acute lymphoblastic leukemia is an important health problem in Kurdistan region and its pattern differs in certain respects from that reported from different regions of the world though comparable in other aspects.

The study recommends implementation of preventive, diagnostic and therapeutic strategies for leukemias in the Kurdistan region.