Detection of helicobacter pylori infection in dyspeptic patients by different sero-bacteriological methods
المؤلفون المشاركون
المصدر
العدد
المجلد 17، العدد 2 (31 ديسمبر/كانون الأول 2008)، ص ص. 17-21، 5ص.
الناشر
تاريخ النشر
2008-12-31
دولة النشر
قطر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
To evaluate invasive (biopsy related) tests and non- invasive (serological) tests in the diagnosis of H.pylori, ninety-two adults (54 male, 38 female) presenting with dyspepsia were studied after classification into two groups on the basis of endoscopical diagnosis ; 46 patients with erosive diseases (gastroduodenal ulcers or gastroduodenal erosions) and 46patients with non-erosive diseases (gastri¬tis or gastroduodenitis).
Sera were testedfor anti-H.pylori IgG and IgM by an immunochromatography card test and ELISA respectively.
Three antral biopsies were taken for biopsy urease test (BUT), bacterial culture and histologi¬cal examination.
Stool samples were obtained from only 30 dyspeptic cases for H.pylori antigen detection (HpSA) by an ELISA method.
H.
pylori was detected in 81 of 92 cases; these were positive by one or more of the gold standard tests (culture, histology and biopsy-urease test).
Histological examina¬tion yielded the highest frequency of microorganism detection (71.7 %), followed by BUT (68.5 %) and then bacterial culture (26.1 %).
In erosive disorders the BUT gave the highest frequency ofpositivity (78.3 %), followed by histological examination (67.4 %), and then bacterial culture (41.3 %) but in non-erosive disorders histological examination gave the highest positive results (76.1 %) fol¬lowed by BUT (58.7 %) and bacterial culture (10.9 %).
The overall sensitivities of BUT, histology and bacterial culture of H.pylori were 77.8 %, 81.5 0% and 29.6% respectively.
Serologically the anti-H.pylori IgG test yielded the highest frequency of positive results (80.4 %), followed by HpSA test (66.7%) and the least positive was anti-H.pylori IgM test (65.2 %).
In the light of the gold standard tests used (biopsy-related tests), the validity of anti-H.pylori IgG test, anti-H.pylori IgM test and HpSA test were determined; the sensitivities being 79 %, 65.4 % and 75 % respectively and their specificities were 9.1 %, 36.4 % and 66.7 % respectively.
The positive and negative predictive values, the positive and negative likelihood ratios of serological tests were also evaluated.
Conclusion : The most sensitive invasive test (biopsy related) andnoninvasive (serological) tests were histologi¬cal examination and IgG immunochromatography card tests respectively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Qibi E. M.& Abd Allah Z. A.. 2008. Detection of helicobacter pylori infection in dyspeptic patients by different sero-bacteriological methods. Qatar Medical Journal،Vol. 17, no. 2, pp.17-21.
https://search.emarefa.net/detail/BIM-366464
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Qibi E. M.& Abd Allah Z. A.. Detection of helicobacter pylori infection in dyspeptic patients by different sero-bacteriological methods. Qatar Medical Journal Vol. 17, no. 2 (Dec. 2008), pp.17-21.
https://search.emarefa.net/detail/BIM-366464
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Qibi E. M.& Abd Allah Z. A.. Detection of helicobacter pylori infection in dyspeptic patients by different sero-bacteriological methods. Qatar Medical Journal. 2008. Vol. 17, no. 2, pp.17-21.
https://search.emarefa.net/detail/BIM-366464
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 21
رقم السجل
BIM-366464
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر