Antisperm antibodies in women with unexplained infertility
المؤلفون المشاركون
المصدر
العدد
المجلد 18، العدد 1 (31 مايو/أيار 2009)، ص ص. 7-12، 6ص.
الناشر
تاريخ النشر
2009-05-31
دولة النشر
قطر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Unexplained infertility occurs in many couples of childbearing age, immune mechanisms have been postu¬lated in this disorder for the last few decades.
Circulating antibodies against spermatozoa present in serum and seminal plasma have been especially implicated.
This autoimmunity against spermatozoa has been investigated in males, while the isoimmunity (in the females) has got low attention.
Fifty women with unexplained infertility and twenty fertile women were involved in this case-control study.
ELISA test was used to detect antisperm antibody (ASA) from cervical mucus (CM) and serum specimens of both groups of women.
CM was collected at mid-cycle period and dissolved mechanically (not by bromeline).
Thirty percent of infertile women have IgG-ASA in their serum and 20 % have IgA-ASA in the CM, while 22 % of fertile women have IgG-ASA in their serum and no fertile women have any titer of IgA-ASA in their CM specimens.
Only CM-IgA-ASA of infertile women showed significant statis-tical correlation with cellular property of CM, which was scored according to Insler score.
It is concluded that ELISA test is more sensitive and specific than microagglutination tests for detection of serum and secreted ASA.
Also, secretory IgA-ASA are more indicative and have potential role in immunological infertility as iso- immunity than IgG-ASA.
Therefore, it is strongly recommended that immunological infertility should be considered as an important cause of infertility and have to gain a special interest by clinicians.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ali N. H.& Flaifil M. S.. 2009. Antisperm antibodies in women with unexplained infertility. Qatar Medical Journal،Vol. 18, no. 1, pp.7-12.
https://search.emarefa.net/detail/BIM-366775
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ali N. H.& Flaifil M. S.. Antisperm antibodies in women with unexplained infertility. Qatar Medical Journal Vol. 18, no. 1 (May. 2009), pp.7-12.
https://search.emarefa.net/detail/BIM-366775
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ali N. H.& Flaifil M. S.. Antisperm antibodies in women with unexplained infertility. Qatar Medical Journal. 2009. Vol. 18, no. 1, pp.7-12.
https://search.emarefa.net/detail/BIM-366775
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 12
رقم السجل
BIM-366775
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر