Virilization in a female neonate due to increased maternal androgens

الملخص EN

Virilization in a female newborn is usually due to congenital adrenal hyperplasia and requires immediate diagnosis and treatment.

A full-term female infant born with ambiguous genitalia was admitted forevaluation.

We identified Praderstage2, normal serum testosterone, normal 17-hydroxyprogesterone and normal female karyotyping (46XX).

The mother had virilization dur¬ing the first trimester and was found to have elevated serum testosterone on the second day of delivery.

High maternal serum testosterone levels can result in viriliza¬tion in a female newborn and we emphasize the need to consider possible underlying maternal pathology in evaluating such cases.