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Newcastle disease vaccine on non avian source
مقدم أطروحة جامعية
مشرف أطروحة جامعية
al-Amin, Muhammad Abd al-Ghaffar
Khayr, Subhi Ahmad Muhammad
الجامعة
جامعة أم درمان الإسلامية
الكلية
كلية الزراعة
القسم الأكاديمي
قسم إنتاج الدواجن
دولة الجامعة
السودان
الدرجة العلمية
دكتوراه
تاريخ الدرجة العلمية
2006
الملخص الإنجليزي
Newcastle disease (ND) is a serious illness worldwide.
The disease was first isolated in the Sudan in the year 1964 (Karar and Mustafa, 1964). The disease caused very high economic losses in poultry industry.
The control of the disease was practiced by vaccination with komarov strain by intranasal route.
Although the vaccine was successfully controlled the disease but by the increase of poultry industry it was found difficult to use the intranasal route.
Nevertheless there are some reactions.
Being a mesogenic it was found that the vaccine induced some reactions shown by the appearance of some clinical ND signs.
Because of this problems trials for development of other vaccines originated from lentogenic strains started.
One of these methods is the administration of lentogenic vaccine strain through drinking water and spray. However, in our study a mesogenic vaccine strain was developed to substitute the milde lentogenic vaccine strain, and the way of demonstration of the mesogenic strain remain the same as the lentogenic vaccine.
The hot mesogenic strain was passaged many times in vero cell lines.
Then characterization of this vaccine strain was conducted to verify the chemical, Biological and culturing in cell and embrynated eggs and chicks.
So the vaccine was a result of plaquing in vero line designated as clone soba. Soba vaccine was used in drinking water, spray and nasal drops.
Chicks were vaccinated at age 7 days and three weeks.
The immune response was tested by (HI)_and ELISA.
After 2 weeks and one month post vaccination. So it was created new methods of vaccination with lentogenic strains via drinking water and spray. This study is to create a msesogenic vaccine strain from Komorov, by isolating strains by passage in vero cells.
After characterization to know chemicals, biological and culturing in cells and embrynated eggs and chicks.
So a vaccine was done from this clone. This vaccine was used in chicks of 7 day of age and three weeks and the immune antibodies were followed by using the three routes (Drinking water, spray and nasal drop).
The spray method was found to be the best.
At the end a new strain was found and compared with the available vaccines to immunity level and safety and simplicity.
The experiment was evaluated by HI and ELISA.
The cost was reduced according to this study.
التخصصات الرئيسية
الموضوعات
عدد الصفحات
78
قائمة المحتويات
Table of contents.
Abstract.
Introduction.
Chapter One : Review.
Chapter Two : Material and methods.
Chapter Three : Results.
Chapter Four : Discussion.
References.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salah, Umar Uthman al-Hasan. (2006). Newcastle disease vaccine on non avian source. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-367633
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salah, Umar Uthman al-Hasan. Newcastle disease vaccine on non avian source. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University. (2006).
https://search.emarefa.net/detail/BIM-367633
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salah, Umar Uthman al-Hasan. (2006). Newcastle disease vaccine on non avian source. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-367633
لغة النص
الإنجليزية
نوع البيانات
رسائل جامعية
رقم السجل
BIM-367633
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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