Correlation of kidney biopsy and clinical manifestations of primary focal and segmental glomerulosclerosis
المؤلفون المشاركون
Tahiri, Dianah
Chehrei, Ali
Samanianpour, Pargol
Hasan Zadah, Amar
Sadrarhami, Shohreh
Seyrafian, Shiva
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 20، العدد 3 (30 يونيو/حزيران 2009)، ص ص. 417-423، 7ص.
الناشر
تاريخ النشر
2009-06-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
To evaluate the correlation of clinical, laboratory, and pathological features at presentation of focal segmental sclerosis (FSGS), we reviewed in a cross sectional study the pathological findings of kidney biopsies in 64 cases of primary FSGS, and correlated them with the clinical and laboratory data obtained at the time of the biopsies.
The data included blood pressure, glomerular filtration rate (GFR), serum albumin, and the level of proteinuria.
The mean level of serum creatinine was significantly higher in the biopsies' findings of synechiae (adhesions) in the Bowman's capsule, interstitial fibrosis, and global scars (P< 0.05), and mean level of GFR was significantly lower with the presence of interstitial fibrosis (P< 0.05).
Furthermore, there was a positive correlation between the level of serum creatinine and global sclerosis (r = 2.21, P = 0.04), and a negative correlation between the level of GFR and global sclerosis(r= 2.01, P= 0.02).
All the patients with renal insufficiency had interstitial fibrosis in their biopsies in comparison of only the 24 patients (48%) of the group without renal insufficiency (P< 0.05).
There was no significant difference between patients with and without hypertension and nephritic-ranged proteinuria.
We conclude that we found a correlation of renal insufficiency in primary FSGS patients with interstitial fibrosis, global scars and the synechiae of Bowman's capsule in their biopsies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tahiri, Dianah& Chehrei, Ali& Samanianpour, Pargol& Hasan Zadah, Amar& Sadrarhami, Shohreh& Seyrafian, Shiva. 2009. Correlation of kidney biopsy and clinical manifestations of primary focal and segmental glomerulosclerosis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 3, pp.417-423.
https://search.emarefa.net/detail/BIM-36804
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tahiri, Dianah…[et al.]. Correlation of kidney biopsy and clinical manifestations of primary focal and segmental glomerulosclerosis. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 3 (Sep. 2009), pp.417-423.
https://search.emarefa.net/detail/BIM-36804
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tahiri, Dianah& Chehrei, Ali& Samanianpour, Pargol& Hasan Zadah, Amar& Sadrarhami, Shohreh& Seyrafian, Shiva. Correlation of kidney biopsy and clinical manifestations of primary focal and segmental glomerulosclerosis. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 3, pp.417-423.
https://search.emarefa.net/detail/BIM-36804
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 422-423
رقم السجل
BIM-36804
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر