Effects of ethanol on the Hippocampus of rat brain

الملخص EN

Ten albino male rats were orally treated daily with 20% and 30% ethanol ( 5 ml ) for 30 days.

Treatment with 30% ethanol caused degeneration of hippocampus cells accompanied by decrease in cells density and tissue dissociation.

Treatment with 20% ethanol resulted in congestion of blood within the blood vessels located in the damaged tissue, fatty changes and microglial aggregation around the damaged neurons.

In conclusion, and according to the protocol employed in the present study, these concentrations of ethanol caused severe damaging effects to the hippocampal formation in rats brain.

Several explanations for these effects were discussed.