Outcome of pregnancy in patients with inactive systemic lupus erythromatosus and minimal proteinuria
المؤلف
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 20، العدد 5 (31 أكتوبر/تشرين الأول 2009)، ص ص. 802-805، 4ص.
الناشر
تاريخ النشر
2009-10-31
دولة النشر
السعودية
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Systemic lupus erythematosus (SLE) is a multisystem disease.
This study was undertaken to assess the outcome of pregnancies in patients with inactive SLE.
We prospectively studied 20 female patients with diagnosis of stable class IV Lupus nephritis followed up at King Abdul Aziz University Hospital, in Jeddah, Saudi Arabia between 1998 and 2008.
Before each pregnancy all the patients had their blood pressure, serum creatinine, creatinine clearance, serology for SLE and 24-hour urine protein excretion measured and then repeated at monthly intervals during the pregnancy.
Statistical analysis was performed using the Wilcoxon signed-rank test.
Despite having negative antinuclear antibody (ANA) significant complications were observed during pregnancy.
The daily proteinuria during 34-36 weeks' gestation was significantly higher (P< 0.05) than during 32 weeks.
Two patients had abortions one stillbirth and 2 required termination of the pregnancy; one due to severe hypertension, and other due to renal impairment.
One patient developed HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome.
14 patients had a successful pregnancy, including 4 requiring a cesarian section.
In conclusion, although no clinical evidence of lupus disease activity was demonstrated pre-conception proteinuria significantly increased during pregnancy along with maternal and fetal complications.
Pregnant females with diagnosis of SLE need a multidisciplinary care during the pregnancy and post-partum period.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shuhayb, Sad. 2009. Outcome of pregnancy in patients with inactive systemic lupus erythromatosus and minimal proteinuria. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 5, pp.802-805.
https://search.emarefa.net/detail/BIM-37420
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shuhayb, Sad. Outcome of pregnancy in patients with inactive systemic lupus erythromatosus and minimal proteinuria. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 5 (Oct. 2009), pp.802-805.
https://search.emarefa.net/detail/BIM-37420
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shuhayb, Sad. Outcome of pregnancy in patients with inactive systemic lupus erythromatosus and minimal proteinuria. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 5, pp.802-805.
https://search.emarefa.net/detail/BIM-37420
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 804-805.
رقم السجل
BIM-37420
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر