The effect of anemia management on chronic renal failure progression
المؤلفون المشاركون
Ghobrial, Imad E.
Salamah, Khalid M.
Shaba, Maha F.
al-Shafae, Najla H.
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 61، العدد 1 (31 مارس/آذار 2013)، ص ص. 37-41، 5ص.
الناشر
تاريخ النشر
2013-03-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Treatment of anemia in children with predialysis chronic kidney disease (CKD) has been facilitated by the administration of recombinant human erythropoietin (rHuEpo).
The aim of this study was to evaluate the effect of rHuEpo on the correction of anemia and to study its effect on the progression of CKD in predialysis patients.
Methods: This study was done at the New Children’s Hospital, Cairo University, included 40 patients with CKD and renal anemia on conservative management.
The patients were divided into two groups; group I (received rHuEpo) and group II (did not receive rHuEpo).
For all patients, clinical assessment and routine laboratory investigation were recorded every 2 weeks, in addition to iron indices and ultrasonography.
Glomerular filtration rate (GFR) was calculated every 2 weeks and the rate of decline of GFR (DGFR) was determined over 6 months preceding starting follow up.
GFR was also determined over a follow up period of 12 months.
Results: There was a statistically significant difference between the initial and final levels of hemoglobin (Hb) and hematocrit (Hct) in group I.
Also, there was a statistically significant difference between the two groups as regards Hb and Hct levels at the end of the study.
The progression of CKD is already slower before T0 (the time of starting rHuEpo administration) in group I and also decreased after T0, with highly statistically significant difference.
Conclusion: The study concluded that rHuEpo therapy is beneficial for correction of renal anemia and its early treatment is a useful intervention for slowing the progression in patients with CKD.
ª 2013 Production and hosting by Elsevier B.V.
on behalf of The Egyptian Pediatric Association.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghobrial, Imad E.& Salamah, Khalid M.& Shaba, Maha F.& al-Shafae, Najla H.. 2013. The effect of anemia management on chronic renal failure progression. Egyptian Pediatric Association Gazette،Vol. 61, no. 1, pp.37-41.
https://search.emarefa.net/detail/BIM-374585
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghobrial, Imad E.…[et al.]. The effect of anemia management on chronic renal failure progression. Egyptian Pediatric Association Gazette Vol. 61, no. 1 (2013), pp.37-41.
https://search.emarefa.net/detail/BIM-374585
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghobrial, Imad E.& Salamah, Khalid M.& Shaba, Maha F.& al-Shafae, Najla H.. The effect of anemia management on chronic renal failure progression. Egyptian Pediatric Association Gazette. 2013. Vol. 61, no. 1, pp.37-41.
https://search.emarefa.net/detail/BIM-374585
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 41
رقم السجل
BIM-374585
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر