Antinuclear antibodies and glutamic acid decarboxylase antibodies in children with refractory epilepsy
المؤلفون المشاركون
al-Sirugi, Hisham
Abd al-Aziz, Sahar A.
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 61، العدد 1 (31 مارس/آذار 2013)، ص ص. 46-51، 6ص.
الناشر
تاريخ النشر
2013-03-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
-Background: Increased prevalence of antinuclear antibodies (ANA) and auto glutamic acid decarboxylase antibodies (GADA) ratio have been reported in patients with epilepsy.
Anti- GAD antibodies (GADA) were first implicated in the pathogenesis of some neurological diseases including epilepsy.
The aim of the study: To determine the occurrence of GADA and ANA in the serum of children with refractory epilepsy.
Patients and methods: Forty children with refractory epilepsy 25 males and 15 females, mean age 9.17 ±3.4 years were selected for this study.
Patients with refractory epilepsy had recurrent seizures for more than 18 months with no more than a 3-month seizure free period during those 18 months and failure of at least two appropriate AEDs with proper doses, good compliance and within normal therapeutic range.
Twenty children with controlled idiopathic epilepsy 15 males and 5 females newly diagnosed as suffering from various types of seizures generalized and partial types, mean age 10.1 ±3.1 years were also included in this study.
These children with idiopathic epilepsy were included in this study for comparison with children with refractory epilepsy as regard to the serum ANA and GADA.
Results: Children with refractory epilepsy had high-serum levels of GADA and ANA in comparison to children with idiopathic epilepsy (P< 0.001), also there was a significant correlation between the duration of seizures and the serum levels of ANA and GADA in children with refractory epilepsy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Aziz, Sahar A.& al-Sirugi, Hisham. 2013. Antinuclear antibodies and glutamic acid decarboxylase antibodies in children with refractory epilepsy. Egyptian Pediatric Association Gazette،Vol. 61, no. 1, pp.46-51.
https://search.emarefa.net/detail/BIM-374641
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Aziz, Sahar A.& al-Sirugi, Hisham. Antinuclear antibodies and glutamic acid decarboxylase antibodies in children with refractory epilepsy. Egyptian Pediatric Association Gazette Vol. 61, no. 1 (2013), pp.46-51.
https://search.emarefa.net/detail/BIM-374641
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Aziz, Sahar A.& al-Sirugi, Hisham. Antinuclear antibodies and glutamic acid decarboxylase antibodies in children with refractory epilepsy. Egyptian Pediatric Association Gazette. 2013. Vol. 61, no. 1, pp.46-51.
https://search.emarefa.net/detail/BIM-374641
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 50-51
رقم السجل
BIM-374641
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر