Comparison between the efficacy of 9 % Hypertonic sodium chloride solution, pentostam and silver nitrate for treatment of cutaneous leishmaniasis

الملخص EN

The study was conducted on 107 patients of cutaneous leishmaniasis, from Dour town, Salahadeen province attending the Dermatology Department of Saddam General Hospital, Tikrit.

Patients were divided to 4 groups for purpose of treatment and comparison, followed up for two months duration.

Group A: treated with intralesional hypertonic sodium chloride solution (9 % HSCS).

Group B: treated with intralesional pentostam injection, 1 cc.

per day for 6 consecutive days.

Group C: treated with silver nitrate cauterization one to two doses of three days interval.

Group D: left without treatment as a control group.

It was found that the efficacy of 9% hypertonic sodium chloride solution and pentostam were 94% and silver nitrate was 78%.

No patient cured among untreated control group.

It was concluded that the efficacy of sodium chloride solution and pentostam was greater than silver nitrate solution.