The role of antimullerian hormone in the diagnosis of poly cystic ovarian syndrom
المؤلف
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 55، العدد 4 (31 ديسمبر/كانون الأول 2013)، ص ص. 373-378، 6ص.
الناشر
تاريخ النشر
2013-12-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting up to 10 % of women of reproductive age.
The cardinal features of PCOS are hyperandrogenism (HA) and oligo-anovulation.
Many work teams recently have relate the severity of PCOS with Anti mullerian hormone (AMH) or antral follicle count (AFC).
Objective : 1) to confirm if there is an increase of serum AMH in our group of patients with PCOS, 2) to relate the AMH level to the follicle status at ultrasound (U / S) in our group of patients, and 3) to search if AMH or AFC can serve as surrogate for the definition of PCOS.
Patients and methods: Twenty five (control) and another 45 participants (with PCOS) were selected for this study.
The control women had a mean age of 32.5 year (yr) and the patients group women had a mean age of 28.4 yr.
Blood samples were collected from all participants, anthropometric measurements were calculated, and transvaginal U / S was performed to measure the AFC during the early follicular phase.
The blood samples were assayed for AMH, follicle-stimulating hormone (FSH), Luteinizing Hormone (LH) and estradiol (E2) and total testosterone (TT).
Results: Basal serum hormonal levels of LH, AMH and TT as well as AFC were significantly higher in the study group than in controls.
While basal serum levels of E2 and FSH show no significant difference between the two groups.
Body mass index (BMI) is significantly higher in PCOS patients.
Basal serum levels of AMH show significant positive correlation with both AFC and basal serum TT levels.
The area under the receiver operating characteristic curve (ROCAUC) for AMH and AFC show significant sensitivity and specificity Conclusion : serum AMH and AFC appear as a sensitive and specific parameter that would probably help in the diagnosis of PCOS.
Both criteria need to be incorporated into the Rotterdam definition for PCOS, and it indicates PCOS only if associated with HA and / or oligo-anovulation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Tai, Hanan A.. 2013. The role of antimullerian hormone in the diagnosis of poly cystic ovarian syndrom. Journal of the Faculty of Medicine Baghdad،Vol. 55, no. 4, pp.373-378.
https://search.emarefa.net/detail/BIM-380434
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Tai, Hanan A.. The role of antimullerian hormone in the diagnosis of poly cystic ovarian syndrom. Journal of the Faculty of Medicine Baghdad Vol. 55, no. 4 (2013), pp.373-378.
https://search.emarefa.net/detail/BIM-380434
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Tai, Hanan A.. The role of antimullerian hormone in the diagnosis of poly cystic ovarian syndrom. Journal of the Faculty of Medicine Baghdad. 2013. Vol. 55, no. 4, pp.373-378.
https://search.emarefa.net/detail/BIM-380434
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 376-378
رقم السجل
BIM-380434
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر