Study of alkaloid extract from citrullus colocynthis fruit and its antimicrobial activity screening

الملخص EN

The antimicrobial activity of alkaloid extracted from Citrullus colocynthis were examined against five local isolates bacteria (Escherichia coli, Staphylococcus aureus, Streptococcus sp., Bacillus subtilis, and Klipsella sp.) using agar disc diffusion method, beside two traditional antibiotics (Amoxicillin and Cephalosporin).

The most active antimicrobial activity of extracted alkaloid were shown against Strep.

sp, the Cephalosporin showed the most antimicrobial activity.

Broth dilution methods were used to determine the minimum inhibitory concentration (MIC) for the extracted alkaloid.

The study showed that MIC values of 600 μg/ ml, 3000 μg/ ml, against Staph.

aureus, and E.

coli isolates respectively