Cytotoxicity and antibacterial effect of 2-(2-hydroxy naphthylazo)‎ phenyl mercuric chloride and 4-(2-hydroxy naphthylazo)‎ phenyl mercuric chloride against some bacterial isolates in vitro

الملخص EN

The 2-(2-hydroxynaphthylazo) phenyl mercuric chloride and 4-(2-hydroxynaphthylazo) phenyl mercuric chloride were evaluated for their biological activity against standard strains of Staphylococcus aureus ATCC25923 and Ecsherichia coli ATCC 25922.

The results showed that there is a potent antibacterial activity for these compounds.

Minimal inhibitory concentration was determined for two compounds, it was 20μg/ml, 40μg/ml for Staph.

aureus, and 50μg/ml, 60μg/m for E.

coli respectively.

Cytotoxicity assay was carried out against human red blood corpuscles, the two compounds exhibited a toxic effect in all used concentrations