Some hematological and biochemical effects of potassium permanganate (KMnO4)‎ on female mice (Mus Musculus L.)‎

الملخص EN

Potassium permanganate (KMnO4) is a strong oxidant salt that is used to dissolve organic material found in water.

To study the effect of (KMnO4) on some physiological parameters in mice (Mus Musculus L.).

Twenty four female mice were subdivided into three groups, one as control group that received intrapretonial 0.1 ml of distilled water, and two treatment groups, one received 0.25 mg and the other received 0.50 mg per mice of (KMnO4) daily during two weeks.

Blood parameters (PCV,Hb,RBC,WBC) showed significant decrease (P<0.01) when compared with control group.

On the other hand, the study of biochemical parameters showed significant increase (P<0.01).

in GOT , and significant decrease (P<0.01) in GPT , and alkaline phosphates , while no effect appeared in RBS , Blood urea, and serum creatinine when compared with the control group (P<0.01).