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Assessment of serum and salivary malondialdehyde in patients with oral lichen planus
المؤلفون المشاركون
Zaydan, Taghrid Fadil
Abbas, Aws Walid
al-Barrak, Abd al-Azim Y. Abbud
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 26، العدد 2 (30 يونيو/حزيران 2014)، ص ص. 99-102، 4ص.
الناشر
تاريخ النشر
2014-06-30
دولة النشر
العراق
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Resulting from the increased production of free radicals and reactive oxygen species and / or a decrease in antioxidant defense leads to damage of biological macromolecules and dysregulation of normal metabolism and physiology.
Oral lichen planus (OLP) is a chronic inflammatory oral mucosal disease of unknown cause.
It has been proven that the imbalances in free radical levels and reactive oxygen species with antioxidants may play a key role in the onset and evolution of several inflammatory oral pathologies.
The aim of this study was to assess the role of oxidative stress in the pathogenesis of OLP through the study of serum and saliva malondialdehyde as a marker of oxidative stress.
Methods : The study included (48) patients with OLP (21) with the reticular form and (27) with erosive form and (32) healthy looking volunteers that were age-matched with the patients.
Serum and saliva malondialdehyde was measured by reacting with thiobarbituric acid under acidic conditions and heating to a pink color that measured spectrophotometricaly at 532 nm.
Results : the mean of serum and saliva malondialdehyde in oral lichen planus patients group was significantly higher than that of control group (p < 0.01 and p < 0.05 respectively) and there was no statistically significant differences in serum and saliva malondialdehyde when compared between reticular and erosive forms (p > 0.05).
The study showed that there was no statistically significant correlation between serum and saliva malondialdehyde levels in OLP patients group (r = 0.053, p > 0.05).
Conclusion : Increased serum and salivary malondialdehyde levels refer to the role of oxidative stress in the pathogenesis of OLP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abbas, Aws Walid& Zaydan, Taghrid Fadil& al-Barrak, Abd al-Azim Y. Abbud. 2014. Assessment of serum and salivary malondialdehyde in patients with oral lichen planus. Journal of Baghdad College of Dentistry،Vol. 26, no. 2, pp.99-102.
https://search.emarefa.net/detail/BIM-387333
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abbas, Aws Walid…[et al.]. Assessment of serum and salivary malondialdehyde in patients with oral lichen planus. Journal of Baghdad College of Dentistry Vol. 26, no. 2 (Jun. 2014), pp.99-102.
https://search.emarefa.net/detail/BIM-387333
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abbas, Aws Walid& Zaydan, Taghrid Fadil& al-Barrak, Abd al-Azim Y. Abbud. Assessment of serum and salivary malondialdehyde in patients with oral lichen planus. Journal of Baghdad College of Dentistry. 2014. Vol. 26, no. 2, pp.99-102.
https://search.emarefa.net/detail/BIM-387333
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 101-102
رقم السجل
BIM-387333
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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