Nigella sativa pretreatment in guinea pigs exposed to cigarette smoke modulates in vitro tracheal responsiveness
المؤلفون المشاركون
Boskabady, Muhammad Husayn
Keyhanmanesh, Rana
Nazimiyah, Husayn
Mazouchian, Husayn
Asl, Muhammad Mahdi Baqiri
Shuar, Mahdi Karimi
Alipour, Muhammad Rida
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 16، العدد 7 (31 يوليو/تموز 2014)، ص ص. 1-5، 5ص.
الناشر
تاريخ النشر
2014-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : In previous studies, the bronchodilator and antitussive effects of Nigella sativa have been demonstrated on guinea pigs.
Objectives : In the present study, the effect of the hydroethanolic extract of N.
sativa on tracheal responsiveness in guinea pigs exposed to cigarette smoke was examined.
Materials and Methods : Three groups of guinea pig models of COPD were given drinking water alone (COPD group), drinking water containing vitamin C (COPD + VC group), and N.
sativa (COPD + NS group).
Tracheal responses to methacholine were measured as effective concentration causing 50 % of maximum response (EC50 M) in control animals (group C) and three groups of guinea pigs with COPD (n = 7, for all groups).
Tracheal responses to 0.1 % ovalbumin in comparison to contraction obtained by 10 μM methacholine were also examined.
Results : The tracheal responsiveness to both methacholine and ovalbumin in guinea pigs with COPD were significantly higher than those of controls (P < 0.001 for both cases).
The tracheal responsiveness in the COPD + VC and the COPD + NS groups to both methacholine and ovalbumin were significantly decreased in comparison to the COPD group (P < 0.05 and P < 0.001, respectively).
Conclusions : These results showed the preventive effect of hydroethanolic extract of N.
sativa on tracheal responsiveness of guinea pig model of COPD, which was as effective as vitamin C.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Keyhanmanesh, Rana& Nazimiyah, Husayn& Mazouchian, Husayn& Asl, Muhammad Mahdi Baqiri& Shuar, Mahdi Karimi& Alipour, Muhammad Rida…[et al.]. 2014. Nigella sativa pretreatment in guinea pigs exposed to cigarette smoke modulates in vitro tracheal responsiveness. Iranian Red Crescent Medical Journal،Vol. 16, no. 7, pp.1-5.
https://search.emarefa.net/detail/BIM-387346
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Keyhanmanesh, Rana…[et al.]. Nigella sativa pretreatment in guinea pigs exposed to cigarette smoke modulates in vitro tracheal responsiveness. Iranian Red Crescent Medical Journal Vol. 16, no. 7 (Jul. 2014), pp.1-5.
https://search.emarefa.net/detail/BIM-387346
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Keyhanmanesh, Rana& Nazimiyah, Husayn& Mazouchian, Husayn& Asl, Muhammad Mahdi Baqiri& Shuar, Mahdi Karimi& Alipour, Muhammad Rida…[et al.]. Nigella sativa pretreatment in guinea pigs exposed to cigarette smoke modulates in vitro tracheal responsiveness. Iranian Red Crescent Medical Journal. 2014. Vol. 16, no. 7, pp.1-5.
https://search.emarefa.net/detail/BIM-387346
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5
رقم السجل
BIM-387346
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر