Serum inflammatory cytokines and depression in coronary artery disease
المؤلفون المشاركون
Taghipour, Ali
Tajfard, Muhammad
Latif, Latifah A.
Muhibati, Muhsin
Rahimi, Hamid Rida
Ismaili, Habib Allah
Mahdipour, Elahe
Davari, Hafizah
Saghiri, Zahrah
Hanachi, Parichehr
Ghayour Mobarhan, Majid
Ferns, Gordon A.
Azizian, Maryam
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 16، العدد 7 (31 يوليو/تموز 2014)، ص ص. 1-7، 7ص.
الناشر
تاريخ النشر
2014-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Severe depression may be accompanied by immune dysregulation and is also associated with increased risk of coronary artery disease (CAD).
Objectives : We investigated serum levels of 10 cytokines and their relationship with depression in patients with cardiovascular diseases as well as healthy subjects in northeast of Iran.
Patients and Methods : The study was carried out on 462 subjects (120 healthy subjects and 342 candidates undergoing angiography).
The healthy subjects were referred for routine annual checkups or pre-employment examinations; they did not have clinically evident CAD.
A questionnaire was used to obtain demographic data and the Beck depression inventory (BDI) was applied to assess depression.
The Evidence Investigator® platform was used for cytokines assays for IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, TNF-α, MCP-1 and IFN-γ, using sandwich chemiluminescent method.
The statistical analysis was performed using SPSS version 11.5.
Results : The mean age was 53.3 ± 11.5, 54.8 ± 11.3, and 59.5 ± 11.3 in healthy, angiography (-), and angiography (+) subjects, respectively (P < 0.05).
There were significant differences in serum levels of IL-4, IL-6, IL-10, and MCP-1 cytokines, comparing subjects with CAD and healthy persons (P < 0.05).
When all subjects were divided to with and without depression regardless of their cardiovascular status, there was a significant difference in serum levels of IL-8 and IL-6 between the groups (P < 0.05).
When the subgroup with features of CAD was selected and divided to those with and without depression, there was also a significant difference in serum levels of IL-8 and TNF-α (P < 0.05).
Conclusions : The positive interaction between depression and CAD was probably mediated by inflammatory mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tajfard, Muhammad& Latif, Latifah A.& Rahimi, Hamid Rida& Muhibati, Muhsin& Ismaili, Habib Allah& Mahdipour, Elahe…[et al.]. 2014. Serum inflammatory cytokines and depression in coronary artery disease. Iranian Red Crescent Medical Journal،Vol. 16, no. 7, pp.1-7.
https://search.emarefa.net/detail/BIM-387619
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tajfard, Muhammad…[et al.]. Serum inflammatory cytokines and depression in coronary artery disease. Iranian Red Crescent Medical Journal Vol. 16, no. 7 (Jul. 2014), pp.1-7.
https://search.emarefa.net/detail/BIM-387619
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tajfard, Muhammad& Latif, Latifah A.& Rahimi, Hamid Rida& Muhibati, Muhsin& Ismaili, Habib Allah& Mahdipour, Elahe…[et al.]. Serum inflammatory cytokines and depression in coronary artery disease. Iranian Red Crescent Medical Journal. 2014. Vol. 16, no. 7, pp.1-7.
https://search.emarefa.net/detail/BIM-387619
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6-7
رقم السجل
BIM-387619
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر